Mice in a Science Lab

🐀💉 Blood of Pikin Rat Dey Add Life Give Old Rat

⬇️ Pidgin ⬇️ ⬇️ Black American Slang ⬇️ English

Na tory wey go shock many pipo, wey scientists bin dey talk say if dem carry di blood of young rat put for di old ones, dem fit live longer by 6 to 9 percent pass di way dem dey live before. Wetin dis one mean be say, na im be like six extra years for pesin wey be normal human being. 🧓🐁

Di ogbonge team of scientists don dey find way to add more life to di old rat by connecting their blood vessels to young rat. Na so di young blood come dey make di old rat dem dey live longer. Dis one come be like say di young blood dey carry something wey dey make life stay long.🧪💡

Wetin dem call joining animals together na ‘parabiosis’, and e don tey wey e don dey since di time of 19th century when French scientists go join two rats together with blood vessel. Dem come use compound from deadly plant test whether e go work, and na im di eyes of both rats come open wide.👀💊

During di 1950s, one professor for Cornell University come try am with young and old rat, dem go tie their body together. Later, di old rats come dey look young again.

Then for early 2000s, dis parabiosis matter come back again. As dem dey use modern-day way study how e be when two animals of different age dey share blood. Dem come find out say di muscles and brain of di old rat come dey fresh again, but di young one come dey old quick quick.🧠🧘

Some dokita come dey use dis small finding to dey do business, dey collect blood plasma from young pipo to treat old-age sickness. Na im Food and Drug Administration come warn dem for 2019 say e get danger inside.❌👨‍⚕️

For many years now, Dr. White and im colleagues dem dey find how dem go take understand di way dis young blood dey make old rat dey young. Dem go connect old rat and young rat for three months — e pass as dem dey do am before — before dem go separate dem. After dem separate, dem come dey look how e be, to see how e fit make dem live longer.🔬📝

As dem dey observe di old rat, dem come see say e be like say di way dem dey old don pause. Two months later, e be like say dem don dey young pass dem mate wey no join body with young rat.

Di young rat wey dem join sef, e come be like say e don dey old quick quick. “Di young rat dey old fast fast, but if we separate di rats, e go come back,” na wetin one expert for biological clocks for Harvard Medical School talk.

Dem publish dis study for di journal wey dem call Nature Aging, and na something wey many pipo like well well. “E dey show say dis effect no be something wey go quick go,” one expert for Stanford University wey no follow for di study talk.📚✅

But one research scientist for University of California, Berkeley, come dey warn say e fit no be so e dey, because another experiment wey dem do last year no show say old rat go live longer after parabiosis. “But at least person dey do di experiment, e no easy,” di dokita talk.🤷‍♂️🔎

Di long way wey dis experiment follow show Dr. White say e fit no be say na di cells of di young rat dey make di old ones fresh. When dem separate dem, di old rats no come dey old again.

E fit be say di bad things wey dey inside di old rat come mix with di blood of di young rat. Or di young blood fit get something wey dey change di cells of di old rat, so dem go dey behave like young cells after dem separate dem.💉🧬

Even with all di tin wey di study show, Dr. Gladyshev no see am as reason make pesin go dey find young human serum put for im body. First, im and im colleagues no know which things dey make up di life-extending mixture for rats, not to talk of human being. Again, injections no be di same thing as to join body with another animal for months. “For my mind, e dey very strange to tink say e fit work,” Dr. Gladyshev talk.🙅‍♂️🚫

Dis na di way e be, as dis discovery show us new thing, e still get way to go before we fit really sabi how e dey make old rat dey live longer, and whether e fit help human beings. But na good start, and di possibilities na something wey fit make we dey look out.🌱🌍


NOW IN BLACK AMERICAN SLANG

🐀💉 Young Mice Blood Makin’ Old Ones Live Longer

Aight, sit tight, ’cause this some wild stuff right here. Scientists are up to somethin’, and they just found that mixin’ blood from young mice into older ones can add life, extendin’ it by 6 to 9 percent. Think about that – six more years for a regular person. 🧓🐁

Now, this crew of science folks, they been connectin’ blood vessels of the young and old mice. And guess what? That youthful blood got the older ones feelin’ fresh and livin’ longer. Like, there’s somethin’ in that young blood that’s all about keepin’ life goin’. 🧪💡

Talkin’ ’bout connectin’ animals, it ain’t a new thing. Folks been doin’ this since way back in the 1800s, like these French cats that linked two rats together. Used some wild plant stuff and both rats’ eyes went big. 👀💊

Back in the 50s, a professor joined young and old rats, stitchin’ ’em together. Old rats started lookin’ all young again.

Fast forward to the 2000s, they started this thing again. Modern times, modern techniques. Old mice gettin’ young, while the young ones start actin’ all old. 🧠🧘

Some docs jumped on this, offerin’ shots of young people’s blood to treat old age issues. But the big health bosses in 2019 were like, “Hold up, y’all, this could be risky.” ❌👨‍⚕️

Now Dr. White and his crew, they been workin’ on this, tryin’ to crack the code of this anti-aging thing. They put an old mouse and a young mouse together for three months. And bam! Older mice livin’ longer. 🔬📝

It ain’t just about livin’ longer, though. These old mice stopped gettin’ old. Two months later, they lookin’ all “younger” than other mice their age.

The young mice? They felt the connection too. Got older, then went back to young when separated. 🧓🔙

People talkin’ ’bout this study, published and all. Even got praise from a big shot at Stanford. 📚✅

But not everyone’s on board. Some are skeptical, pointin’ out other studies that don’t match up. 🤷‍♂️🔎

What’s goin’ on here? Dr. White thinks it ain’t just about the young cells fixin’ the old ones. After cuttin’ ’em loose, old mice still kept their young look.

Maybe the young blood’s washin’ away the bad stuff in the old mice, or teachin’ old cells new tricks. 💉🧬

But don’t get it twisted. This ain’t no green light for human shots of young blood. We ain’t sure what’s in that mouse magic potion, and gettin’ an injection ain’t the same as bein’ hooked up to another critter for months. Dr. Gladyshev’s like, “I ain’t buyin’ it.” 🙅‍♂️🚫

So there it is, peeps. Science servin’ up somethin’ intriguing. Got ways to go, but it’s an interesting beginning. The future? Who knows? Could be somethin’ big. 🌱🌍


NOW IN ENGLISH

🐀💉 Young Mice’s Blood Extends Life in Older Mice

In a surprising discovery, scientists have revealed that infusing the blood of young mice into older ones can extend their lifespan by 6 to 9 percent. This increase is roughly equivalent to six additional years for an average human being. 🧓🐁

A highly skilled team of scientists has been working on a method to extend the lives of older mice by connecting their blood vessels to those of younger mice. This infusion of youthful blood has led to the older animals living longer, suggesting that the young blood contains substances that promote longevity.🧪💡

The practice of joining animals together, known as ‘parabiosis’, has a long history, dating back to the 19th century when French scientists connected two rats through their blood vessels. To verify their connection, they used a compound from a deadly plant, resulting in the dilation of both rats’ pupils.👀💊

During the 1950s, a professor at Cornell University experimented with parabiosis by connecting young and old rats, stitching them together. Subsequently, the older rats appeared to become younger.

Then in the early 2000s, parabiosis underwent a revival. Using modern-day techniques, scientists studied the effects of sharing blood between animals of different ages. They found that the muscles and brains of old mice were rejuvenated, while the younger ones showed signs of premature aging.🧠🧘

Some doctors capitalized on these preliminary results, offering injections of blood plasma from young people to treat diseases related to old age. The Food and Drug Administration warned against such treatments in 2019, citing potential risks.❌👨‍⚕️

For several years, Dr. White and his colleagues have been refining parabiosis procedures to better understand its anti-aging effects in mice. They connected an old and young mouse for three months, twice as long as typical experiments, before carefully separating them. After observing the animals’ recovery, they found that the older mice lived longer.🔬📝

They observed that the aging process in the old mice seemed to have paused. Two months later, these mice appeared to be “younger” than untreated ones of the same age.

The young mice were also affected, aging more rapidly but reversing the effect once separated. “The young mice rapidly become older, but if we separate the mice, it goes back,” said an expert in biological clocks at Harvard Medical School.

This study was published in the journal Nature Aging and has been well-received by many experts. “It shows that this effect is not transient,” commented a Stanford University expert not involved in the study.📚✅

However, a research scientist at the University of California, Berkeley, cautioned that a similar experiment last year did not show that old mice lived longer after parabiosis. “But at least someone is doing the experiments, which is not easy,” the scientist noted.🤷‍♂️🔎

The long-term impact of this experiment led Dr. White to believe that it’s not solely the young mice’s cells rejuvenating the old ones. After separation, the old mice maintained their youthful state.

One possibility is that harmful compounds in the old mice were diluted by the young mice’s blood. The young blood might also contain molecules that reprogram the old mice’s cells, so they continued to act like younger cells after separation.💉🧬

Despite the study’s findings, Dr. Gladyshev did not see it as a justification for using young human serum. He and his colleagues are uncertain about what makes up the life-extending mixture in mice, let alone in humans. Furthermore, injections differ significantly from being joined to another animal for months. “To me, it’s very strange to think it could work,” Dr. Gladyshev said.🙅‍♂️🚫

This is where the discovery stands, revealing exciting possibilities but also acknowledging that there’s much to be learned about how it extends the life of old mice, and whether it can be applied to humans. However, it’s an intriguing start, and the potential is something to watch for in the future.🌱🌍

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