Genetics DNA

🐈‍⬛ Genes to Kolobi di Kitten Boom! 💥💉

Plenti cats dey run evriwe, but e be like say di popuashun don too much pass us! Dem dey born plenti kittens wey full di strez. E no easy for dem at all, dem dey chop plenti sikness, dey run from pipo wey fit chop dem, and even car wey fit nack dem! No be small wahala! 🐱🐱🐱

Plenti obodo pipo, especially di ones for United States, dey work sote dem no dey tire to catch dis cats, dey sterilize dem, and kom release dem back to wia dem come from. But na wahala full ground to control dis stray cat popuashun. Some places, especially for Africa, no get beta kain money and resos to fit do am. Na so so wahala full ground! 🇺🇸🌍💸👨‍⚕️🐱

Dis mata don dey ginger pipo make dem find anoda way to solve di wahala wey stray cats dey cause. Dem don try many surgical ways, but e neva gel. No successful tin for ground. But weytin be di new tori for town? Dem talk say dem fit use gene tins take control dis stray cat popuashun. E fit be di solution wey we dey find! 💉🐈‍⬛📚🚼🚫

Na inside one new study wey Nature Communications publish dem tok dis tori. Dem giv cats one shot of gene therapy wey stop dem from belle for at least two years. No be small tin o! Di study small shaa, na onli six female cats dem use for di study, and three no take di shot. 💉🐈‍⬛📚🚼🚫

Dis shot dey carry one gene wey enter di cat muscle, and e cause dem to produce one kain thing wey dem dey call anti-Müllerian hormone (AMH). Dis substance dey make di eggs no fit grow for di belle. E be like magic! 🧬💪🥚🚫

Di scientists dem dey talk say dem still need do more research to confam say dis tin dey safe, but if big-big studies show say dis treatment (wey be di first gene therapy for animals) dey work wella and no get wahala, dat mean say pipo no go need do sterilization surgeries again. 🐈‍⬛🔍🏥👩‍⚕️🚫

One researcher, David Pépin, wey dey work for Massachusetts General Hospital for Boston, dey tok say e dey study dis AMH tin first to take treat ovarian cancer. But as e dey tok, e kon decide say make e test di tin for ovary. Wen e take dis hormone give rats, dia ovary come shrink like pesin wey neva enta puberty. Dis one show say AMH fit control birth. 🏥👨‍🔬🐁👶💊

Dr. Pépin dey reason say e fit help women wey no fit use birth control pills wey get progesterone and estrogen sake of dem health condition, or women wey wan preserve dem fertility wen dem get cancer. But dem no sure say dem fit use AMH as gene therapy for humans. “But e dey perfect to take control cat population,” e tok. 👨‍⚕️💊👩‍⚕️🤰🐈‍⬛🌍

Dis doctor and di oda doctor, Dr. Swanson, dey plan one big study wey dem fit carry go FDA (Food and Drug Administration) make dem fit use di therapy for cats. Dem dey test di therapy for small-small cats wey just dey eight weeks old, and even for dogs sake of dog stray population no be small matter too. 🐱🐶💉🧪📝🏢

Dis study don make many pipo happy. One vet wey dey work for University of Florida College of Veterinary Medicine, Julie Levy, talk say e go make sense well well if dem fit send technician go field go give cats di shot and kom release dem. She talk say dem don put plenti money for di Mata wey Michelson Foundation dey invest for. Dem no wan make dem dey do surgery again. 🐕‍🦺💰💉🐈‍⬛

But she also talk say dem still need to learn plenti tins from big-big study. Dem need to know how long di shot go last, if e dey safe well well, and how many cats e go fit protect from belle so. E no go fit protect all. Dem no go fit trap all cats. E go still hard well well to control popuashun. 🐈‍⬛🕳️💉🙅‍♀️

For now, we fit onli wait and see. Who know, maybe soon we go get new way to control stray cat popuashun? We go dey look with our eye! 🙏🐈‍⬛🔮

NOW IN ENGLISH

🐈‍⬛ Genes to Curb the Kitten Boom 💥💉

There’s this interesting study that’s all about using genetic engineering to control the population of stray cats. Despite the many pet cats in our homes, there’s a vast number of strays out there, breeding at an exponential rate! 🐱🐱🐱

These stray cats lead a tough life, facing a variety of diseases, predators, and fast-moving vehicles. Moreover, they themselves are predators, killing numerous birds and small creatures each year. 🐈‍⬛🦠🚗🐦🐭

In the United States, many volunteers work tirelessly to catch these cats, get them sterilized at clinics, and then release them back to where they were found. But controlling the stray cat population is an expensive and complex task. There are many areas, particularly outside of the U.S. and Europe, where there simply aren’t enough resources or funding for this. 🇺🇸🇪🇺💸👨‍⚕️🐱

William Swanson, an animal researcher at the Cincinnati Zoo & Botanical Garden, says that people have been looking for a surgical alternative for decades, but no viable solutions have been found yet. 👨‍🔬🏞️🐱🚫🔪

However, a potential solution might be on the horizon. In a study published in the journal Nature Communications, they gave cats a shot of gene therapy that prevented them from getting pregnant for at least two years. The study was small, involving only six female cats that received the shot and three that didn’t. 💉🐈‍⬛📚🚼🚫

This shot carries a gene that enters muscle cells and causes them to produce a substance called anti-Müllerian hormone, or AMH, which inhibits egg development in the ovaries. 🧬💪🥚🚫

The researchers maintain that more research is needed to ensure safety, but if larger studies show that the treatment—the first gene therapy for animals—is effective and safe throughout the cat’s lifespan, then sterilization surgeries may no longer be necessary. 🐈‍⬛🔍🏥👩‍⚕️🚫

David Pépin, a reproductive biologist at Massachusetts General Hospital in Boston, was originally studying AMH as a potential treatment for ovarian cancer, but then decided to examine its effects on ovaries. When he administered the hormone to mice, their ovaries shrunk to a prepubescent size, suggesting AMH could serve as a form of birth control. 🏥👨‍🔬🐁👶💊

Dr. Pépin believes it could benefit women who are unable to take birth control pills containing progesterone or estrogen due to health issues, or it might help women preserve their fertility during cancer treatments. However, using AMH in humans as a gene therapy might not be feasible. “But it’s actually the perfect tool to control cat overpopulation,” he says. 👨‍⚕️💊👩‍⚕️🤰🐈‍⬛🌍

Dr. Pépin and Dr. Swanson are planning a larger study that could potentially gain approval from the Food and Drug Administration for the therapy’s use in cats. They are also testing the therapy on kittens from the age of eight weeks and on dogs, as there’s a significant population of stray dogs as well. 🐱🐶💉🧪📝🏢

This study has excited many in the field. Julie Levy, a veterinarian at the University of Florida College of Veterinary Medicine in Gainesville, says, “Wouldn’t it be great if we could send out a technician into the field to inject cats and then let them go?” She points out that the study demonstrates how the Michelson Foundation is investing heavily in finding a non-surgical way to control the stray cat and dog population. 🐕‍🦺💰💉🐈‍⬛

She does note, however, that there is much to learn from a larger study, such as how long the shot lasts, if it is truly safe, and how many cats it will effectively protect from pregnancy, as it won’t be 100 percent effective.

Others express that it might not be so straightforward. If the shot proves to be effective, long-lasting, and cheaper than spaying and neutering surgeries, it could be extremely valuable, says Autumn Davidson, a vet at Cornell’s College of Veterinary Medicine in Ithaca, N.Y. However, the animals must be captured to administer the shot, and some cats are quite adept at avoiding traps, making population control still a difficult task. 🐈‍⬛🕳️💉🙅‍♀️

For now, we must wait and see. Who knows, maybe soon there will be a new method to control the stray cat population? 🙏🐈‍⬛🔮

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